Cruises from Colon, Central America Cruises from Colon, Colon Cruise Deals

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Colon, Panama Highlights

Lots to do!

The vast Panama Canal is a remarkable sight to behold.

Featured Cruises from Colon, Panama

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$93.94/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$100.51/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$101.36/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$101.36/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$101.94/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$106.51/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$102.51/night

Royal Caribbean | Grandeur of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Oranjestad, Aruba • Willemstad, Curacao • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $101.55 in taxes and expenses.

7 Night Southern Caribbean

Round Trip Colon, Panama

Starting at

$115.45/night

Royal Caribbean | Serenade of the Seas

Ports: Colon, Panama • Cartagena, Colombia • Day at Sea • Willemstad, Curacao • Oranjestad, Aruba • Day at Sea • Day at Sea • Colon, Panama + View More

Pricing above includes $104.14 in taxes and expenses.

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American Discount Vacations is proud to offer the best deals possible on all cruises from Colon, Panama. Backed by our "Low Price Guarantee," and powered by our team of expert travel agents, we're sure to exceed your expectations when booking your next cruise departing from Colon, Panama!

Cruises From Colon, Panama